Technical Data
MRP4 (Multidrug Resistance-associated Protein 4, ATP-binding Cassette Sub-family C (CFTR/MRP) Member 4, ATP Binding Cassette Sub-family C Member 4, ABCC4, bA464I2.1, Canalicular Multispecific Organic Anion Transporter ABC Superfamily, EST170205, MRP/cMOAT
Suitable for use in Immunocytochemistry, Immunohistochemistry, Western Blot and Flow Cytometry. Other applications not tested.

Recommended Dilution:
Immunocytochemistry (acetone fixed): 1:20-50
Immunohistochemistry (acetone fixed frozen): 1:20
Western Blot: 1:20-50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
1ml-20CBlue IceHumanRat
200ug immunoglobulin/ml.
Fusion protein containing the E. coli maltose binding protein and a fragment of the human MRP4 protein corresponding to aa372-431.
Supplied as a liquid in 0.7% BSA, 0.09% sodium azide.
Recognizes human orthologue of the transporter molecule (Mrp4). Species Crossreactivity: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Mrp4 confers resistance to topotecan and acts as a double agent in protecting the brain from chemotherapy Markos Leggas, Masashi Adachi, George L. Scheffer, Daxi Sun, Peter Wielinga, Guoqing Du, Kelly E. Mercer, Yanli Zhuang, John C. Panetta, Brad Johnston, Rik J. Scheper, Clinton F. Stewart, and John D. Schuetz. Mol Cell Biol, Sept. 2004, Vol. 24, No.17, p 7612-7621.