Technical Data
M4700-06
Mucin 1 (MUC1 Glycoprotein, CD227)
Description:
Mucins are heavily glycosylated glycoproteins, which constitute the major components of mucus which cover the surface of epithelial tissues. Nine distinct epithelial mucin genes (Muc-1, 2, 3, 4, 5AC, 5B, 6,7 and 8) have been identified. Various immunohistochemical and in situ hybridization studies have shown that these mucins are differentially expressed in epithelia with cell-type specificity. Muc-5AC and Muc-6 glycoproteins are the first two mucins found in superficial epithelium and Muc-6 glycoprotein is found in the deep glands.

Applications:
Suitable for use in Immunohistochemistry (frozen sections), Immunofluorescence, and Immunometric assays. Other applications have not been tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Hybridoma:
X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20C or colder. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG11.B.876Affinity Purified
SizeStorageShippingSourceHost
1mg4C (-20C Glycerol)Blue IceHumanMouse
Concentration:
Immunogen:
High molecular weight (>300kDa) glycoprotein from human milk-fat globule molecule.
Purity:
>90%. Purified by chromatography on protein A Sepharose. Purity is tested by electrophoresis.
Form
Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
Specificity:
Reacts with human MUC1 Glycoprotein.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.