Cellular Localization: Plasma membrane
Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
| Not determined|
|Purified porcine cardiac m2 muscarinic acetylcholine receptor.|
|Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.|
|This antibody is specific for the m2 mAChR subtype. Species Crossreactivity: Crossreacts with Human, Rat, Mouse and porcine. Does not crossreact with Chicken.|
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
This product has been used in:Luetje CW et al. Isolation and characterization of monoclonal antibodies specific for the cardiac muscarinic acetylcholine receptor. Biochemistry 26:6892-6 (1987). <3427051> Wreggett KA & Wells JW Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors. J Biol Chem 270:22488-99 (1995). <7673239>Wang P et al. Muscarinic acetylcholine receptor subtypes mediating urinary bladder contractility and coupling to GTP binding proteins. J Pharmacol Exp Ther 273:959-66 (1995). <7752101>|