Technical Data
M9520-13C
Muscarinic Acetylcholine Receptor M2 (Chrm2, CHRM-2, 7TM Receptor, FLJ43243, HM2, MGC120006, MGC120007)
Description:
Cellular Localization: Plasma membrane

Applications:
Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG18L847Ascites
SizeStorageShippingSourceHost
125ul-20CBlue IcePorcineMouse
Concentration:
Not determined
Immunogen:
Purified porcine cardiac m2 muscarinic acetylcholine receptor.
Purity:
Ascites
Form
Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
Specificity:
This antibody is specific for the m2 mAChR subtype. Species Crossreactivity: Crossreacts with Human, Rat, Mouse and porcine. Does not crossreact with Chicken.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
This product has been used in:Luetje CW et al. Isolation and characterization of monoclonal antibodies specific for the cardiac muscarinic acetylcholine receptor. Biochemistry 26:6892-6 (1987). Wreggett KA & Wells JW Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors. J Biol Chem 270:22488-99 (1995). Wang P et al. Muscarinic acetylcholine receptor subtypes mediating urinary bladder contractility and coupling to GTP binding proteins. J Pharmacol Exp Ther 273:959-66 (1995).