Technical Data
M9758-02L
Myelin Basic Protein (MBP)
Description:
Myelin basic protein accounts for about 30% of the proteins in myelin from the central nervous system. It is best known for its capacity to induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity; though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Myelin basic protein is expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry (Formalin/paraffin): 1:100-1:200 for 30 minutes at RT. No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues.
Optimal dilutions to be determined by the researcher.

Positive Control: Brain

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
250ul-20CBlue IceHumanRabbit
Concentration:
Not Determined
Immunogen:
Myelin basic protein isolated from human brain. Cellular Localization: Cytoplasmic
Purity:
Purified
Form
Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Specificity:
Recognizes human Myelin Basic Protein.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Penneys N S, et al. Arch Pathol Lab Med 1983;107:302. 2. Mogollon R, et al. Canc 1984; 53:1190.