Technical Data
Myelin Basic Protein (MBP)
Myelin basic protein accounts for about 30% of the proteins in myelin from the central nervous system. It is best known for its capacity to induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity; though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Myelin basic protein is expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves.

Immunohistology (Formalin/paraffin): (Use Ab at 1:50 to 1:100 for 30 min at RT) No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues.

Positive Control: Brain

Cellular Localization: Cytoplasmic

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20C or colder. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
250ul-20CBlue IceHumanRabbit
Not determined
Myelin basic protein isolated from human brain.
Purified antibody fraction from rabbit anti-serum.
Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA and 0.09% sodium azide.
Recognizes Myelin Basic Protein. Species Crossreactivity: Human.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Penneys N S, et al. Arch Pathol Lab Med 1983;107:302
2. Mogollon R, et al. Canc 1984; 53:1190.