Technical Data
M9758-02L
Myelin Basic Protein (MBP)
Description:
Myelin basic protein accounts for about 30% of the proteins in myelin from the central nervous system. It is best known for its capacity to induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity; though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Myelin basic protein is expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves.

Applications:
Immunohistology (Formalin/paraffin): (Use Ab at 1:50 to 1:100 for 30 min at RT) No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues.

Positive Control: Brain

Cellular Localization: Cytoplasmic

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20C or colder. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabPurified
SizeStorageShippingSourceHost
250ul-20CBlue IceHumanRabbit
Concentration:
Not determined
Immunogen:
Myelin basic protein isolated from human brain.
Purity:
Purified antibody fraction from rabbit anti-serum.
Form
Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA and 0.09% sodium azide.
Specificity:
Recognizes Myelin Basic Protein. Species Crossreactivity: Human.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Penneys N S, et al. Arch Pathol Lab Med 1983;107:302
2. Mogollon R, et al. Canc 1984; 53:1190.