Technical Data
Myelin Basic Protein (MBP)
Myelin basic protein accounts for about 30% of the proteins in myelin from the central nervous system. It is best known for its capacity to induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity; though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Myelin basic protein is expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves.

Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry (Formalin/paraffin): 1:100-1:200 for 30 minutes at RT. No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues.
Optimal dilutions to be determined by the researcher.

Positive Control: Brain

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
250ul-20CBlue IceHumanRabbit
Not Determined
Myelin basic protein isolated from human brain. Cellular Localization: Cytoplasmic
Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Recognizes human Myelin Basic Protein.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Penneys N S, et al. Arch Pathol Lab Med 1983;107:302. 2. Mogollon R, et al. Canc 1984; 53:1190.