Technical Data
N0018-69P
NALP9 (NACHT, LRR and PYD Domains-containing Protein 9, Nucleotide-binding Oligomerization Domain Protein 6, PYRIN and NACHT-containing Protein 12, NLRP9, NOD6, PAN12)
Description:
NALP9 is a 991aa containing cytoplasmic protein belonging to the NLRP family with aDPIN domain, three LRR (leucine-rich) repeats and a NACHT domain. Also called NOD6, NALP9 is a novel intracellular protein involved in inflammation and apoptosis. NALP9 may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, which activates the pro-inflammatory caspases, Caspase-1 and Caspase-5.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20CBlue IceHumanRabbit
Concentration:
Not determined.
Immunogen:
Synthetic peptide corresponding to aa859-875 KTLKLGHNEIGDTGVRQ of human NALP9.
Purity:
Serum
Form
Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
Specificity:
Recognizes human NALP9. Species sequence homology: monkey, mouse, rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Tschopp, J. et al. Nature Rev. Molec. Cell Biol. 4:95-104 (2003). 2. Inohara, N. et al. Nature Rev. 3:371-382 (2003).