Technical Data
N2050-10C
Nerve Growth Factor, beta Recombinant, Human (NGFb)
5ug
20ug
100ug
20ug
100ug
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Technical Data |
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N2050-10C |
Nerve Growth Factor, beta Recombinant, Human (NGFb) |
5ug 20ug 100ug |
| Growth Factors, Cytokines | Storage: -70°CShipping: Blue Ice |
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Human NGF-beta is a neurotrophic factor related to BDNF, NT-3 and NT-4. Human NGF-beta acts as a neurotrophic factor through its receptor beta-NGFR, and is involved in the development and sustaining the sensory and sympathetic nervous systems. H-NGFbeta also is also involved in the growth and differentiation of B lymphocytes and B-cell survival. Human NGF-beta is a noncovalently disulfide-linked homodimer, consisting of 121 amino acids with a molecular weight of two 13.6kD polypeptide monomers. Endotoxin: <0.01ng/ug or <0.1EU/ug as per LAL AA Sequence: MSSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRR Biological Activity: Biological acitivity is determined by the ability to stimulate chick E9 DRG neurite growth. The ED50 is < 1.0ng/ml, corresponding to a specific activity of > 1x10e6 units/mg. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O, aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 13.6 kD |
Source: Recombinant, human, E. coli Purity: 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Form: Supplied as a lyophilized powder. Reconstitute with sterile dH2O PBS to 0.1-1mg/ml, which can be further diluted into other aqueous solutions. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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