Technical Data
Nidulin (Methylustin)
Biochemicals Storage: 4C/-20CShipping: Blue Ice
Nidulin is a depsidone produced by several fungal species with potent and selective antibacterial activity. While literature relating to nidulin is limited, it is closely related to folipasatin and unguinol identified as inhibitors of phospholipase A2, arachidonic acid release from rat polymorphonuclear leukocytes and nitrendipine binding to porcine heart membrane. While showing some calcium blocking attributes these metabolites have potential as antiinflammatory agents.

Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility

CAS Number:

Molecular Formula:

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Source: Emericella sp.
Purity: > 99% by HPLC
Form: White solid

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Nidulin and ustin; two chlorine-containing metabolic products of Aspergillus nidulans. Dean F.M. et al. Nature. 1953, 172, 344. 2. Studies on fungal products XVIII. Isolation and strucutres of a new fungal depsidone related to nidulin and a new phthalide from Emercicella unguis. Kawahara N. et al. Chem. Pharm. Bull. 1988, 36, 1970. 3. Folipastatin, a new depsidone compound from Aspergillus unguis as an inhibitor of phospholipase A2. Hamano K. et al. J. Antibiot. 1992, 45, 1195.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.