Nonidet-P40 substitute (Igepal CA-630, T-DET O-series, ethoxylated octylphenol, T-DET O-9)
|Biochemicals||Storage: RTShipping: RT|
Nonidet-P40 is an anhydrous liquid nonionic surface- active agent produced by the reaction of octyl phenol with 8.5-9.5 moles of ethylene oxide. Nonidet-P40 (NP-40) is a nonionic surfactant used in the isolation of membrane complexes. This product has been reformulated to be eco-friendly. The only observable differences are that the viscosity and handling characteristics are somewhat modified. Due to its nonionic structure, this product is compatible with anionic surfactants and is stable in the presence of acids, bases, and salts. It should not be mixed with concentrated oxidizing or reducing agents since the mixture of these compounds with organic compounds could form a potentially explosive mixture. Nonidet-P40 is an effective emulsifier for solvents such as xylene.
Appearance: Colorless to pale yellow, clear, viscous liquid
pH (1% aqueous): 5-7
Specific Gravity (25°C): 1.065
Viscosity (cP, 25°C): ~246
Surface Tension (0.1% aqueous, 25°C): ~30 dynes/cm
Flash Point (PMCC): 260°C
Pour Point: 7°C
Cloud Point (1% aq): 64-68°C
Surface Tension (1% aq): 35 dynes/cm
Odor: Mild Aromatic
Handling and Toxicity:
Nonidet-P40 is regarded as non-hazardous. However, it is considered to possess low acute oral and skin penetration. It should not be used in products for internal use. Caution: This product causes eye irritation. Direct contact would likely result in corneal injury which might persist for a week or longer. Permanent damage is not likely to occur. However, if in contact with skin or eyes, flush with excess water and consult your physician.
Nonidet-P40 nonionic surfactants are stable non-corrosive products in their anhydrous state. They can be stored in plain steel tanks with piping, valves, and pumps of the same metal. Aqueous solutions of Nonidet-P40 must be stored in stainless steel or plastic lined tanks. The octyl phenol-ethylene oxide adducts are slightly hygroscopic. Where necessary, guard against atmospheric moisture pick-up, an inert gas blanket may be used.
Igepal CA-630; T-DET O-series; ethoxylated octylphenol; T-DET O-9; Nonidet P40 substitute
Nonylphenylpolyethylene glycol; Polyethyleneglycol-p-isooctylphenyl ether; Octylphenoxy polyethoxy ethanol; Polyethylene Mono(nonylphenyl)ether Glycols; Polyoxyethylene (9) Nonylphenyl Ether; nonyl phenol ethoxylate; nonylphenyl polyethyleneglycol ether, nonionic; polyethylene glycol 450 nonyl phenyl ether, nonionic surfactant; Tergitol NP-9; polyethylene glycol 450 nonyl phenyl ether; Ethoxylated nonylphenol;
alpha(nonylphenyl)-omega-hydroxypoly(oxy-1,2-ethanediyl); polyethylene glycols mono(nonylphenyl)ether; macrogol nonylphenyl ether; nonoxinol; polyoxyethylene(n)-nonylphenyl ether; nonylphenoxypolyethoxyethanol; nonylphenyl polyethylene glycol ether; nonoxynol; Makon; T-DET-N; surfionic n; sterox; arkopal N-090; carsonon N-9; igepal co-630; neutronyx 600; PEG-9 nonyl phenyl ether; protachem 630; rewpol hv-9; polyoxyethylene nonyl phenol; Glycols, polyethylene, mono(nonylphenyl) ether; Nonylphenol polyethylene glycol ether; Nonylphenol, polyoxyethylene ether; Nonylphenoxypoly(ethyleneoxy)ethanol; POE nonylphenol; Polyoxyethylene nonylphenol; POE (10) nonylphenol
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
US Biological application references: 1. Chung, M.Y. et al., (2010) J Nutr Biochem. 12:1200-1206 2. Merchant, M. L. et al., (2009) Proteomics-Clinical Applications 4:84-96. 3. Shah, S.K. et al., (2010) Neurogastroenterology & Motility 22:1132–e290. 4. Burton, M.D. and Johnson, R.W. (2011) Brain, Behavior, and Immunity doi:10.1016/j.bbi.2011.10.008.