Technical Data
N6000-05G
NT-3 (Neurotrophin 3, Neurotrophin-3, NT3, NTF3, HDNF, MGC129711, Nerve Growth Factor 2, Nerve Growth Factor-2, NGF2, NGF-2, Neurotrophic Factor)
Description:
Seems to promotes the survival of visceral and proprioceptive sensory neurons.

Cellular Localization:
Secreted protein.

Tissue Specificity:
Brain and peripheral tissues. Belongs to the NGF-beta family.

Applications:
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
20ug-20°CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
A synthetic peptide (YAEHKSHRGEY) as part of human (aa: 139-149), mouse and rat NT3 protein conjugated to BSA.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a lyophilized powder. Reconstitute in 50ul of sterile water.
Specificity:
A crossreactivity of less than 0.1% to mouse NGF, recombinant human BDNF and NT4/5 has been shown by dot blot. Species Crossreactivity: This antiserum is known to react with rat, chicken and human NT3.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Zouh et al. (1996) Mol. Neurobio. 13(3): 185-97 ; Rush et al. (1997) Clin. Exp. Pharmacol. 24: 549-55 ; Tafreshi et al. (1998) Neurosci. 83(2): 373-80