Technical Data
NT-3 (Neurotrophin 3, HDNF, NGF-2, Nerve growth factor-2)
NT-3 is a neurotrophic factor structurally related to NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6kD polypeptide monomers (238 total aa residues).

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Recommended Secondary Antibodies:
I1906: IgY, Chicken Pab Rb xCh
I1906-10: IgY, Chicken (HRP) Rb xCh
I1906-12: IgY, Chicken (FITC) Rb xCh
I1906-14: IgY, Chicken (AP) Rb xCh
I1906-01: IgY, (HRP) Gt xCh

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
500ug-20CBlue IceHumanChicken
Human NT-3 mixed peptides
Purified by precipitation.
Supplied as a liquid.
Recognizes human NT-3. Species Crossreactivity: Mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.