Technical Data
8-Oxoguanine DNA Glycosylase, Human, Control Peptide (OGG1)
Molecular Biology Storage: -20CShipping: Blue Ice
Human 8-Oxoguanine DNA Glycosylase (hOGG1) is involved in the excision of 7, 8-dihydro-8-oxoguanine produced as a result of DNA damage. This gene has been localized on human chromosome 3p25. Several forms of hOGG protein have been cloned differing in lengths (351-424 aa) (1).

An 18aa peptide close to the N-terminus of human OGG1 was selected for antibody production (1, 2).

Sequence Homology:
The peptide sequence has 100% homology with various forms of human OGG (1, 2). It has sequence homology of 55% (10/18aa) with the mouse and only 38% (7/18aa) with rat OGG (3).

ELISA: Use 50-100ng control peptide/well

Storage and Stability:
Lyophilized powder may be stored at 4C for short-term only. Reconstitute to nominal volume by adding sterile buffer or dH2O and store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Purity: Purified
Concentration: ~1mg/ml
Form: Supplied as a lyophilized powder.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Aburatani H et al (1997) gene accession # U88620; Radicella JP et al (1997) PNAS 94, 8010-8015; Rosenquist TA et al (1997) PNAS 94, 7429-7434
2. Kuo FC et al (1997) J Exp Med. (in press).
3. Tani M et al (1997) gene accession # AF012912; Prieto-Alamo MJ et al (1997) gene accession # AF029690.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.