Technical Data
O5700-25B
8-Oxoguanine DNA Glycosylase (OGG1)
Description:
Human 8-Oxoguanine DNA Glycosylase (hOGG1) is involved in the excision of 7, 8-dihydro-8-oxoguanine produced as a result of DNA damage. This gene has been localized on human chromosome 3p25. Several forms of hOGG protein have been cloned differing in lengths (351-424 aa) (1).

Applications:
ELISA (1:10-50K; using 50-100ng control peptide/well. See O5700-25A.)

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabSerum
SizeStorageShippingSourceHost
100ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
An 18aa peptide close to the N-terminus of human OGG1 (coupled to KLH). Species Sequence Homology: Mouse - 55% (10/18aa); Rat - 38% (7/18aa)
Purity:
Serum
Form
Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
Specificity:
Recognizes human OGG1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Aburatani H et al (1997) gene accession # U88620; Radicella JP et al (1997) PNAS 94, 8010-8015; Rosenquist TA et al (1997) PNAS 94, 7429-7434

2. Kuo FC et al (1997) J Exp Med. (in press).

3. Tani M et al (1997) gene accession # AF012912; Prieto-Alamo MJ et al (1997) gene accession # AF029690.