Technical Data
O7030-11A
Opioid Receptor, delta, CT, aa360-372
Description:
The function of the delta-opioid receptors has not been determined. However, recent studies in rodents have linked delta-opioid receptor antagonists with prevention of morphine tolerance and dependence without relinquishing mu-opioid antinociception. In general, opioids modulate numerous central and peripheral processes, including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.

Applications:
Suitable for use in Immunoprecipitation. Other applications have not been tested.

Recommended Dilution:
Immunoprecipitation: 1:250-12000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at 4C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol, PBS, 10mg/ml BSA., aliquot and store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul4C (-20C Glycerol)Blue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to the carboxyl terminal of the delta opioid receptor (carrier protein).
Purity:
Serum.
Form
Supplied as a lyophilized powder. Reconstitute with 100ul sterile, 40-50% glycerol, PBS, 10mg/ml BSA.
Specificity:
Shown to be specific for the C-terminal of the delta opioid receptor. Recognizes Delta Opioid Receptor (aa360-372) 100%; Delta Opioid Receptor: 60%; Mu Opioid Receptor: 0%; Kappa Opioid Receptor: 0%. Species crossreactivity: Rat
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.