Technical Data
O7030-36C
Opioid Receptor 1C, mu (MOR1C)
Description:
Three types of opioid receptors have been cloned -- mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Several C-terminal splice variants have been identified for the Mu Opioid Receptor (MOR1) including MOR1C. These splice variants appear to differ in their pharmacological selectivity as well as their membrane trafficking.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry: 1:5000-1:10000. Use perfusion fixed tissues. Perfusion: Calcium free Tyrodes solution, paraformaldehyde-picric acid fixative, and 10% sucrose in PBS as a cryo-protectant.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
50ul-20CBlue IceRatRabbit
Concentration:
Not determined
Immunogen:
Synthetic peptide corresponding to the aa. sequence KSCMDRGMRNLLPDDGPRQE.
Purity:
Serum
Form
Supplied as a liquid in 0.05% sodium azide.
Specificity:
Recognizes rat MOR-1C. Species Crossreactivity: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.