Osteocalcin (Bone Gla Protein) is a 49aa single chain vitamin K dependent protein (MW 5.8kD), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget’s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.
Suitable for use in Immunohistochemistry and Immunofluorescence. Other applications not tested.
Immunohistochemistry (Frozen): 1:50-1:500
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
| Not Determined|
|Highly purified mouse osteocalcin|
|Supplied as a liquid, 0.09% sodium azide.|
|Recognizes intact mouse osteocalcin. Reacts with a site at the carboxyl terminal of Osteocalcin. Does not react with Rat, Human, Bovine, monkey, elk or chicken.|
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
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