Technical Data
O8060-21K
Osteocalcin (Bone-Gla-Protein, BGLAP, BGP, Bone gamma Carboxyglutamate Protein, Gamma Carboxyglutamic Acid-containing Protein, PMF1)
Description:
Osteocalcin (Bone Gla Protein) is a 49aa single chain vitamin K dependent protein (MW 5.8kD), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pagets disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.

Applications:
Suitable for use in Immunohistochemistry and Immunofluorescence. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry (Frozen): 1:50-1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20CBlue IceMouseGoat
Concentration:
Not Determined
Immunogen:
Mouse osteocalcin
Purity:
Serum
Form
Supplied as a liquid, 0.1% sodium azide.
Specificity:
Recognizes intact mouse osteocalcin. Reacts with a site at the carboxyl terminal of Osteocalcin. Does not react with Rat, Human or Bovine.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Matsumoto T et al., J Exp Med 207: 2207-23 (2010)