Technical Data
Osteoprotegerin, ID (Tumor Necrosis Factor Receptor Superfamily Member 11B, Osteoclastogenesis Inhibitory Factor, TNFRSF11B, OCIF, OPG)
Osteoprotegerin (OPG, or osteoclastogenesis inhibitory factor) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401aa with molecular weight of 55kD as a monomer and 110kD as a disulfide-linked dimer. Osteoprotegerin acts as a soluble factor in the regulation of bone mass and may be beneficial in the treatment of osteoporosis associated with increased osteoclast activity.

Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PabIgGAffinity Purified
100ug-20CBlue IceHumanRabbit
Not determined
Synthetic peptide corresponding to 16aa near the center of human osteoprotegerin
Purified by immunoaffinity chromatography.
Supplied as a lyophilized powder, 0.5% BSA, 0.02% sodium azide. Reconstitute with 200ul sterile dH2O.
Recognizes human Osteoprotegerin.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.