Technical Data
O8236
8-Oxoguanine Hydrochloride (8-Hydroxyguanine Hydrochloride; 2-Amino-6,8-dihydroxypurine Hydrochloride)
500mg
Molecular Biology Storage: -20CShipping: RT
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda.

Melting Point: >350 C (decomposes)

Solubility: Alkaline Water, DMSO

Method for Determining Identity: Proton NMR spectroscopic snalysis and mass spectrometric analysis

TLC Conditions:
SiO2; Methanol: Water: Triethylamine (9:1:1). Visualized with UV and AMCS; Single spot; Rf=0.3

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Formula:
C5H6ClN5O2

Molecular Weight:
203.59
Purity: ~95%
Form: Supplied as an off-white solid

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards:
Due to the potential danger associated with the use of some of United States Biological biochemicals, all products should be handled by qualified personnel only, trained in laboratory procedures, and familiar with potential hazards. Information is not available on the possible hazards of many experimental compounds. The absence of a warning must not be interpreted as indication of safety. The ultimate responsibility for the proper handling of any and all chemicals lies with the user. All goods sold by United States Biological carry the condition that liability for any injury, loss or damage whatsoever to persons or real property resulting from the handling of the said goods lies with the user. Acceptance of our goods binds the customer to these terms.
1. Avkin, S., et al.: Mutat. Res., 510, 81 (2002). 2. Niimi, N., et al.: Biochem., 48, 4239 (2009). 3. Muftuoglu, M., et al.: J. Biol. Chem., 284, 9270 (2009).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.