Technical Data
P1800-80A
PEG10 (Retrotransposon-derived Protein PEG10, Embryonal Carcinoma Differentiation-regulated Protein, Mammalian Retrotransposon-derived Protein 2, Myelin Expression Factor 3-like Protein 1, MEF3-like Protein 1, Paternally Expressed Gene 10 Protein, Retrotr
Description:
Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter.

Applications:
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:10,000
Western Blot: 1:500-1:2000
Immunohistochemistry: 1:200-1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 1:200
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG14C10A7Ascites
SizeStorageShippingSourceHost
50ul-20CBlue IceHumanMouse
Concentration:
Not determined
Immunogen:
Recombinant corresponding to human PEG10.
Purity:
Ascites
Form
Supplied as a liquid, 0.03% sodium azide.
Specificity:
Recognizes human PEG10.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.