Cellular Localization: Cytoplasmic
Suitable for use in Western Blot. Other applications not tested.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
| Not determined|
|Recombinant fragment (amino acids 305-559 of Chicken Paxillin). Epitope: Monoclonal Anti-Paxillin recognizes an epitope located in the LIM1 domain of the paxillin molecule.|
|Supplied as liquid tissue culture supernatant, 15mM sodium azide.|
|Species Crossreactivity: Human, Rat, bovine, Chicken and Hamster.|
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
Brown MC et al. Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding. J Cell Biol 135:1109-23 (1996). <8922390>Clark EA & Brugge JS Integrins and signal transduction pathways: the road taken. Science 268:233-9 (1995). <7716514>Hynes RO Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69:11-25 (1992). <1555235>|