Technical Data
P3113-92A
Paxillin (Paired Box Protein Pax-1, HuP48, PAX 1, PAX1, PXN, FLJ16691, FLJ23042, HUP48)
Description:
Paxillin is one of the key components of integrin signaling. Tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal reorganization. Paxillin is phosphorylated by another focal adhesion component, focal adhesion kinase (FAK), at tyrosine 118. Phospho-Tyr118 may provide a docking site for recruitment of other signaling molecules to focal adhesions.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanRabbit
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to human Paxillin at C-terminus.
Purity:
Purified by affinity chromatography.
Form
Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 50% glycerol.
Specificity:
Recognizes human Paxillin. Species Crossreactivity: mouse and rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.