		Technical Data
P3113-92A	Paxillin (Paired Box Protein Pax-1, HuP48, PAX 1, PAX1, PXN, FLJ16691, FLJ23042, HUP48)

Description:
Paxillin is one of the key components of integrin signaling. Tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal reorganization. Paxillin is phosphorylated by another focal adhesion component, focal adhesion kinase (FAK), at tyrosine 118. Phospho-Tyr118 may provide a docking site for recruitment of other signaling molecules to focal adhesions.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to human Paxillin at C-terminus.

Purity:

Purified by affinity chromatography.

Form

Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 50% glycerol.

Specificity:

Recognizes human Paxillin. Species Crossreactivity: mouse and rat.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.