		Technical Data
P3352-15A	PRDX3 (Thioredoxin-dependent Peroxide Reductase, Mitochondrial, Peroxiredoxin-3, Peroxiredoxin III, PRX III, Antioxidant Protein 1, AOP-1, Protein MER5 Homolog, HBC189, AOP1)

Description:
PRDX3 is a protein with antioxidant function and is localized in the mitochondrion. This protein is involved in redox regulation of the cell and protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.

Applications:
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:2000
Immunohistochemistry (Formalin-fixed, paraffin-embedded): 1:250
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Purified

Size		Storage	Shipping	Source	Host
50ul		-20°C	Blue Ice	Human	Rabbit

Concentration:

As reported

Immunogen:

Recombinant corresponding to PRDX3 human fragment protein (without mitochondrial leader sequence), expressed in E. coli.

Purity:

Purified

Form

Supplied as a liquid in HEPES, 0.15M sodium chloride, 0.01% BSA, 0.03% sodium azide, 50% glycerol.

Specificity:

Recognizes human PRDX3. Species sequence homology: mouse and rat

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.