Technical Data
P4072-03L
Phosphodiesterase 4C (Phosphodiesterase 4C cAMP-specific, Phosphodiesterase Type 4C, PDE4C, cAMP Specific 3' 5' Cyclic Phosphodiesterase 4C, DPDE1, MGC126222, PDE21, Phosphodiesterase E1 Dunce Homolog, Phosphodiesterase E1 Dunce Homolog Drosophila)
Description:
Applications:
Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Western Blot: 1:1000-1:2000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanRabbit
Concentration:
~0.5mg/ml
Immunogen:
Synthetic cyclic peptide (carboxy-terminal peptide common to all PDE4C proteins).
Purity:
Purified by immunoaffinity chromatography.
Form
0.02% Thimerosal / Merthiolate
Specificity:
This antibody detects 3 isoforms of PDE4C subclasses (PDE4C1, PDE4C2 and PDE4C3). Species Crossreactivity: Human.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Zhang HT et al. Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism. Neuropsychopharmacology 23:198-204 (2000). Beavo JA Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol Rev 75:725-48 (1995). Farooqui SM et al. Antibodies against synthetic peptides predicted from the nucleotide sequence of D2 receptor recognize native dopamine receptor protein in rat striatum. J Neurochem 57:1363-9 (1991).