		Technical Data
P4072-07Q	PDE7B, ID (cAMP-specific 3',5'-cyclic Phosphodiesterase 7B)

Description:
Phosphodiesterase 7B, a cAMP-specific phosphodiesterase, has been shown to affect cAMP-mediated neural activity and cAMP metabolism in the brain. PDE7B activity is inhibited by dipyridamole, IBMX, and SCH51866. At least three splice variants have been isolated for PDE7B from rats and they show tissue specific expression patterns.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 1.25-2.5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
50ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~1mg/ml

Immunogen:

Synthetic peptide corresponding to 18aa from internal region of human PDE7B.

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in PBS, 0.1% sodium azide.

Specificity:

Recognizes human PDE7B. Species sequence homology: mouse (94%) and rat (94%).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.