Technical Data
P4130-02D
Pick1 (Protein Interacting with PRKCA 1)
Description:
Pick1 is thought to be involved in the organization and localization of a number of membrane proteins (such as AMPA receptors) containing the PDZ recognition sequence. It has been shown that Pick1 binds phosphoinositide lipids using the Bin/amphiphysin/Rvs (BAR) domain. This step is critical for the targeting function of Pick1, its ability to move AMPA receptors to membrane surfaces and the induction of long-term signal depression.

Applications:
Suitable for use in Western Blot. Other applications have not been tested.

Recommended Dilutions:
Western Blot: 0.5ug/ml detects Pick1 on 10ug of rat brain membrane tissue lysate.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2a,k11C251Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceRatMouse
Concentration:
~1mg/ml
Immunogen:
Recombinant protein corresponding to rat Pick1.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150 mM sodium chloride, 0.05% sodium azide.
Specificity:
Recognizes rat Pick1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.