Technical Data
P4256-68K
Plasmodium falciparum MSP1 (P. falciparum, Malaria)
Description:
Plasmodium falciparum is a protozoan parasite that causes malaria in humans. Malaria caused by P. falciparum has high mortality rates and is the most common in sub-Saharan Africa. The parasite is transmitted by Anopheles mosquitoes. Merozoites are the result of asexual reproduction of the parasite in the hepatocytes. They are released from hepatocytes and infected erythrocytes to infect other erythrocytes. MSP1 is the most abundant protein on the surface of merozoites and is involved in parasite invasion of the erythrocyte. It has long been considered a promising candidate for a vaccine against malaria. Some studies have shown that naturally acquired antibodies to a cleavage product of MSP1 can be linked to a reduced risk of clinical malaria.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Hybridoma:
Sp2/0 myeloma cells with spleen cells from Balb/c mice.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2a10F297Affinity Purified
SizeStorageShippingSourceHost
200ug-20CBlue IceMouse
Concentration:
~1mg/ml
Immunogen:
Plasmodium falciparum MSP1.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Specificity:
Recognizes the merozoite surface protein 1 of Plasmodium falciparum.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.