		Technical Data
P4296-06F	PML (Probable Transcription Factor PML, RING Finger Protein 71, Tripartite Motif-containing Protein 19, PML, MYL, RNF71, TRIM19)

Description:
PML protein is a zinc finger transcription factor expressed as three major transcription products due to alternative splicing. The t(15;17)(q22;q11-q12) chromosomal trans-location of the retinoic acid receptor alpha gene occurs in virtually all cases of acute promyelocytic leukemia.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Serum

Size		Storage	Shipping	Source	Host
100ul		-20°C	Blue Ice	Human	Rabbit

Concentration:

Not determined.

Immunogen:

Synthetic peptide corresponding to aa628-647 (TPDAEPHSEPPDHQERPAVH) of human TRIM19 gamma.

Purity:

Serum.

Form

Supplied as a liquid, 0.025% sodium azide, 50% glycerol.

Specificity:

Recognizes human PML. Species Crossreactivity: chimpanzee.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Reymond,A., Meroni,G., Fantozzi,A., Merla,G., Cairo,S., Luzi,L., Riganelli,D., Zanaria,E., Messali,S., Cainarca,S., Guffanti,A., Minucci,S., Pelicci,P.G. and Ballabio,A. The tripartite motif family identifies cell compartments. EMBO J. 20 (9), 2140-2151 (2001).