		Technical Data
P9052-40D1	PCSK9 (NARC-1, LDLCQ1, Proprotein convertase subtilisin/kexin type 9, Hypercholesterolemia, Autosomal dominant 3, Neural apoptosis regulated convertase 1, Proprotein convertase subtilisin/kexin type 9, HCHOLA3, NARC1, FH3)

Description:
Applications:
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:16000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to CRSRHLAQASQELQ of human PCSK9.

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Specificity:

Recognizes human PCSK9.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Blesa S, et al. A new PCSK9 gene promoter variant affects gene expression and causes autosomal dominant hypercholesterolemia. J Clin Endocrinol Metab. 2008. 2. Lambert G, et al. Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment. Clin Chem. 2008 Jun; 54(6):1038-45.