Technical Data
P9053-26H4
Prostaglandin E Receptor EP1 (Prostaglandin E Receptor 1 (Subtype EP1) 42kD, Prostaglandin E2 Receptor EP1 Subtype, PGE2 Receptor EP1 Subtype, PGE Receptor EP1 Subtype, PTGER1, EP1, Prostanoid EP1 Receptor)
Description:
Prostaglandin E receptor EP1 is a member of the Prostanoid Receptor subfamily. Along with several other receptor subtypes (EP2, EP3, and EP4), it mediates the diverse biological effects of prostaglandin E2 (PGE2). PGE2 has been implicated in numerous processes, including immune response modulation, male erectile function, cervical and colon cancer, induction of labor, control of blood pressure, bone resorption, and asthma. Prostaglandin E receptor EP1 expression has been documented in kidney and kidney vessels. ESTs have been primarily isolated from kidney, pancreas, and thymus libraries.

Applications:
Suitable for use in Immunofluorescence, Immunohistochemistry and Immunocytochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (paraffin): 17ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
Human Kidney, Renal tubules

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to the 1st cytoplasmic domain of human EP1.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
Specificity:
Recognizes human EP1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.