Technical Data
PSMA5, NT (Proteasome Subunit alpha Type-5, Proteasome Zeta Chain, Macropain Zeta Chain, Multicatalytic Endopeptidase Complex Zeta Chain)
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PMA5 is a member of the peptidase T1A family, that is a 20S core alpha subunit.

Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As reported
Synthetic peptide selected from the N-terminal region of human PSMA5 (KLH).
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, 0.09% sodium azide.
Recognizes human PSMA5.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Beausoleil,S.A., Nat. Biotechnol. 24(10), 1285-1292 (2006). 2. Gregory,S.G., Nature 441(7091), 315-321 (2006). 3. Beausoleil,S.A., Proc. Natl. Acad. Sci. USA 101(33), 12130-12135 (2004). 4. Conticello,S.G., Curr. Biol. 13(22), 2009-2013 (2003). 5. Yu,X., Science 302(5647), 1056-1060 (2003).