Technical Data
P9076-08A
PSMA6, ID (Proteasome Subunit alpha Type-6, 27kD Prosomal Protein, PROS-27, p27K, Multicatalytic Endopeptidase Complex iota Chain, Macropain iota Chain, Proteasome iota Chain, PROS27)
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Technical Data |
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P9076-08A |
PSMA6, ID (Proteasome Subunit alpha Type-6, 27kD Prosomal Protein, PROS-27, p27K, Multicatalytic Endopeptidase Complex iota Chain, Macropain iota Chain, Proteasome iota Chain, PROS27) |
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Description: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This protein is a member of the peptidase T1A family, that is a 20S core alpha subunit. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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