Technical Data
P9076-16B
PSMB6, CT (Proteasome Subunit beta Type-6, Proteasome delta Chain, Macropain delta Chain, Multicatalytic Endopeptidase Complex delta Chain, Proteasome Subunit Y, LMPY)
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Technical Data |
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P9076-16B |
PSMB6, CT (Proteasome Subunit beta Type-6, Proteasome delta Chain, Macropain delta Chain, Multicatalytic Endopeptidase Complex delta Chain, Proteasome Subunit Y, LMPY) |
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Description: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an TP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB6 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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