Technical Data
P9078-38E
PSMB1, CT (Proteasome gamma Chain, Multicatalytic Endopeptidase Complex Subunit C5, Macropain Subunit C5, Proteasome Component C5, Proteasome Subunit beta Type-1, PSC5)
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Technical Data |
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P9078-38E |
PSMB1, CT (Proteasome gamma Chain, Multicatalytic Endopeptidase Complex Subunit C5, Macropain Subunit C5, Proteasome Component C5, Proteasome Subunit beta Type-1, PSC5) |
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Description: PSMB1 is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. Applications: Suitable for use in ELISA, Flow Cytometry, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Flow Cytometry: 1:10-1:50 Immunohistochemistry: 1:50-1:100 Western Blot: 1:100-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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