Technical Data
R1100-07B
RANTES, Recombinant, Mouse (Regulated on Activation, Normal T-cell Expressed and Secreted)
5ug
20ug
Growth Factors, Cytokines Storage: -20°CShipping: Blue Ice
Recombinant Mouse Rantes produced in E. coli is a single, non-glycosylated polypeptide chain containing 68 amino acids and having a molecular mass of 7876 Dalton. Recombinant murine Rantes is purified by proprietary chromatographic techniques.

AA Sequence:
SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS

Biological Activity:
Recombinant Rantes is fully biologically active when compared to standard. The activity is determined by the ability to chemoattract total human lymphocytes and murine T-cells at a concentration between 1-10ng/ml.

Storage and Stability:
Store desiccated below -20°C. Upon reconstitution, the liquid can be stored at °4C between 2-7 days and for future use, below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid freeze-thaw cycles.

Molecular Weight:
7.88kD
Source: E. coli
Purity: 95% as determined by RP-HPLC and SDS-PAGE. Endotoxin: 0.1ng/ug (1EU/ug).
Form: Supplied as a lyophilized powder without additives. Reconstitute with sterile ddH2O to a concentration 0.1mg/ml. Working dilutions can be made in aqueous buffer.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Role of platelet-derived chemokines (RANTES and ENA-78) after stem cell transplantation. Transpl Immunol 2006 Apr;15(4):247-53. 2. Early prediction of sepsis-induced disseminated intravascular coagulation with interleukin-10, interleukin-6, and RANTES in preterm infants. Clin Chem 2006 Jun;52(6):1181-9. 3. Rat peritoneal mast cells release regulated upon activation normal T cell expressed and secreted (RANTES) after TNF-alpha activation. J Biol Regul Homeost Agents 2005 Jul-Dec;19(3-4):130-5. 4. Preclinical evaluation of synthetic -2 RANTES as a candidate vaginal microbicide to target CCR5. Antimicrob Agents Chemother 2006 Apr;50(4):1497-509. 5. Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities. J Immunol 2006 Mar 15;176(6):3788-95. 6. Serum levels of IL-6 and its soluble receptor, TNF-alpha and chemokine RANTES in scorpion envenomed children: their relation to scorpion envenomation outcome. Toxicon 2006 Mar 15;47(4):437-44.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.