Technical Data
R1120-35
Rap2B (Member of RAS oncogene family, Ras-related protein Rap-2b precursor)
|
Technical Data |
|
R1120-35 |
Rap2B (Member of RAS oncogene family, Ras-related protein Rap-2b precursor) |
|
|
Description: Rap2B is a member of the small GTPase superfamily and ras family of proteins. Unlike normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B has a threonine residue in that position. This change makes the intrinsic GTPase activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer period of time than normal ras proteins. Aggregation of platelets by thrombin results in the activation of Rap2B in a Ca 2+ and PI3 kinase-dependent manner. Applications: Suitable for Western Blot. Other applications not tested. Storage: Lyophilized samples are stable for twelve months from date of receipt when stored at -20°C to -70°C. Upon reconstitution, the antibody can be stored at 2°-8°C for 1 month without detectable loss of activity. Reconstituted antibody can also be aliquotted and stored frozen at -20°C to -70°C in a manual defrost freezer for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles. |
|
|||||||||||
|
||||||||||||
|
||||||||||||
|
||||||||||||