Technical Data
R1595-02K
Respiratory Syncytial Virus (RSV) (HRP)
Description:
Applications:
Suitable for use in ELISA, Immunohistochemistry and Neutralization. Other applications not tested.

Recommended Dilution:
Immunohistochemistry: Paraffin sections
Neutralization: Ethanol-fixation is not recommended.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
1ml-20°CBlue IceGoat
Concentration:
As reported
Immunogen:
Human RSV isolate.
Purity:
Purified by affinity chromatography.
Form
Supplied as a liquid in PBS, 10mg/ml BSA, 0.002% Thimerosal. Labeled with horseradish peroxidase (HRP).
Specificity:
Recognizes all RSV viral antigens. Reacts well with bovine isolates. Does not react with Para 1-3, Influenza A & B or Adenovirus by IFA. Negative against HEp-2 cells and WI-38 cells.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Bitko, V., et al., (2007), “Nonstructural Proteins of Respiratory Syncytial Virus Suppress Premature Apoptosis by an NF-kB-Dependent, Interferon-Independent Mechanism and Facilitate Virus Growth”, Journal of Virology, 81(4): 1786-1795

2. Weltzin, R., et al., (1994), “Intranasal Monoclonal Immunoglobulin A against Respiratory Syncytial Virus Protects against Upper and Lower Respiratory Tract Infections in Mice”, Antimicrobial Agents and Chemotherapy, 38(12): 2785-2791

3. Ramaswamy, M., et al., (2004), “Specific Inhibition of Type I Interferon Signal Transduction by Respiratory Syncytial Virus”, Am. J. Respir. Cell Mol. Biol., 30: 893-900

4. Gitiban, N., et al., (2005), “Chinchilla and Murine Models of Upper Respiratory Tract Infections with Respiratory Syncytial Virus”, Journal of Virology, 79(10): 6035-6042

5. Wright, P.F., et al., (2005), “Growth of Respiratory Syncytial Virus in Primary Epithelial Cells from the Human Respiratory Tract”, Journal of Virology, 79(13): 8651-8654

6. Monick, MM., et al., (2001), “Respiratory Syncytial Virus Infection Results in Activation of Multiple Protein Kinase C Isoforms Leading to Activation of Mitogen-Activated Protein Kinase”, The Journal of Immunology, 166: 2681-2687

7. Monick, MM., et al., (2005), “Activation of the Epidermal Growth Factor Receptor by Respiratory Syncytial Virus Results in Increased Inflammation and Delayed Apoptosis”, The Journal of Biological Chemistry”, 280(3): 2147-2158