Technical Data
R2032-22
Ristocetin A Sulfate (Ristocetin, Ristomycin III, Spontin, Riston)
10mg
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Technical Data |
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R2032-22 |
Ristocetin A Sulfate (Ristocetin, Ristomycin III, Spontin, Riston) |
10mg |
| Biochemicals | Storage: -20°CShipping: Blue Ice |
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Ristocetin A is a potent antibacterial glycopeptide antibiotic but was withdrawn for clinical use following a high incidence of thrombocytopenia. Further investigation found that ristocetin A induced platelet aggregation by binding to a factor absent in people suffering from von Willebrand's disease and lead to the use of ristocetin A as an important diagnostic aid. Solubility: Soluble in water, methanol and DMSO Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. CAS Number: 11140-99-1 Molecular Formula: C95H110N8O44·H2SO4 Molecular Weight: 2166.0 |
Source: Amycolatopsis sp. Purity: 95% by HPLC Form: Supplied as a white solid Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Ristocetin A and B, two new antibiotics. Isolation and properties. Philip, J.E., et al., Antibiot. Annu. 699 (1955). 2. Ristocetin - a new tool in the investigation of platelet aggregation. Howard, M.A., et al., Throm. Diath. Haemorrh. 26: 362 (1971).
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