Technical Data
Rotavirus, ICP, Late Structural Virion Antigens
Rotavirus is a virus that infects the bowels and is the most common cause of gastroenteritis in infants. 7 major groups have currently been identified, 3 of which infect humans (groups A, B and C). Its genome consists of 11 segments of double stranded RNA held in the inner core of the three layered, icosahedral virion particle. The genome codes for 6 virus proteins (VP1,2,3,4,6,7) and 6 non-structural proteins (NSP1-6). Outer capsid proteins are VP4 and VP7, inner capsid -VP6 and core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection; therefore, multiple serotypes of rotavirus mean multiple opportunities for infection.

Suitable for use in Immunofluorescence. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
1ml-20CBlue IceGoat
Nebraska calf diarrhea virus.
Supplied as a liquid in PBS, 0.09% sodium azide.
Recognizes rotavirus and is specific for ICPs and late structural (virion) antigens. Exhibits 90% cross-reactivity with human rotavirus and does not react with HEp-2 cells or WI-38 cells in immunofluorescence. Species sequence homology: human, 90%.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.