Technical Data
R3000-15A
Rotavirus
Description:
Rotaviruses, members of the family Reoviridae, are a major cause of diarrhea in young mammals.
Human rotaviruses, the major etiological agents of severe infantile diarrhea worldwide, display very diverse and complex serotypic specificities. Rotaviruses are 70nm, non enveloped viruses comprised of a triple layered protein capsid; Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection. Therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.

Applications:
Suitable for use in ELISA and IFA. Other applicaations not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Matched Pair:
Capture: R3000-15B
Detection: R3000-15A

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2b9B123Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouse
Concentration:
~0.1mg/ml
Immunogen:
Purified Rhesus Rotavirus (RRV).
Purity:
Purified by Protein A chromatography. >90% pure.
Form
Supplied as a liquid in 0.01M PBS, pH 7.2, 0.1% sodium azide.
Specificity:
Recognizes the intact virus of strains RRV, WA, SA-11 and bovine. Immunostains infected cells. Does not react with Influenza A, Influenza B, RSV, Parainfluenza 1, 2 & 3, Adenovirus, M pneumonia, H. pylori and Mammalian cells.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.