Technical Data
SARS, Spike Protein, NT (Severe Acute Respiratory Syndrome, SARS-CoV, SARS Associated Coronavirus)
A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139kD protein and the major surface antigen of the virus, to the angiotensin- converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.

Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
50ug-20CBlue IceRabbit
Synthetic peptide corresponding to aa at the amino-terminus of the SARS Spike glycoprotein.
Supplied as a liquid in PBS, 0.02% sodium azide.
Recognizes SARS Spike glycoprotein.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Marra MA, et al (2003) Science. 300:1399-404. 2. Rota PA, et al (2003) Science. 300:1394-9. 3. Navas-Nartin SR (2004) J Neurovirol. 10:75-85. 4. Li W, et al (2003) Nature. 426:450-4.