		Technical Data
S1001-21	Serotonin Receptor 5A (5-Hydroxytryptamine 5A Receptor, 5-Hydroxytryptamine Receptor 5A, 5-HT5A, 5-HT-5A, 5HT5A Receptor, 5-HT5A Receptor, 5-HT5AR, HTR5A, MGC138226)

Description:
5HT5A receptor is a G protein coupled receptor (GPCR) in the serotonin receptor family. HT receptors interact with the neurotransmitter and peripheral signal mediator serotonin. In particular, 5-hydroxytryptamine (5HT) receptors mediate the effects of serotonin in its role as the endogenous ligand and in pharmaceutical and hallucinogenic drugs. In addition, 5HT receptors affect the release and activities of other neurotransmitters such as glutamate, dopamine, and GABA.

Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
Western Blot: >1:100
Immunohistochemistry: 1:100-1:300 in PBS/0.03% Triton X-100 – Bn/Av-HRP Technique
Optimal dilutions to be determined by the researcher.

Positive Control:
Rat cortex and hippocampus.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ul		-20°C	Blue Ice	Rat	Rabbit

Concentration:

Not Determined

Immunogen:

Synthetic peptide sequence corresponding to aa17-34 of the rat 5-HT5A receptor

Purity:

Purified by affinity chromatography.

Form

Supplied as a liquid.

Specificity:

Recognizes rat Serotonin Receptor 5A. Species Crossreactivity: mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.