Technical Data
S1001-21A
Serotonin Receptor 5A (5-HT5AR)
Description:
5HT5A receptor is a G protein coupled receptor (GPCR) in the serotonin receptor family. HT receptors interact with the neurotransmitter and peripheral signal mediator serotonin. In particular, 5-hydroxytryptamine (5HT) receptors mediate the effects of serotonin in its role as the endogenous ligand and in pharmaceutical and hallucinogenic drugs. In addition, 5HT receptors affect the release and activities of other neurotransmitters such as glutamate, dopamine, and GABA.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (FFPE): 5ug/ml. Heat induced antigen retrieval using citrate buffer, pH 6.0 is recommended.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide (16aa) of human 5HT5A receptor. Epitope: N-terminus. Species sequence homology: monkey 94%, marmoset 88%. No homology with other human proteins except TRIOBP 44% and SNCG 44%.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.1% sodium azide.
Specificity:
Recognizes Human 5-HT5A Receptor (HTR5A). Species Crossreactivity: gorilla and gibbon
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.