Technical Data
S1001-21D
Serotonin Receptor 5A (5-HT5AR)
Description:
5HT5A receptor is a G protein coupled receptor (GPCR) in the serotonin receptor family. HT receptors interact with the neurotransmitter and peripheral signal mediator serotonin. In particular, 5-hydroxytryptamine (5HT) receptors mediate the effects of serotonin in its role as the endogenous ligand and in pharmaceutical and hallucinogenic drugs. In addition, 5HT receptors affect the release and activities of other neurotransmitters such as glutamate, dopamine, and GABA.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 0.05-0.2ug/ml
Western Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
40ug-20CBlue IceHumanRabbit
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide (KLH). derived from the 3rd intracellular domain loop of human 5HT5A receptor (Swiss Prot P47898).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a lyophilized powder in PBS, pH 7.4, 0.02% sodium azide.
Specificity:
Recognizes endogenous levels of human 5HT5A protein. Species sequence homology: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.