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Technical Data |
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S1013-34A |
Sialoprotein, Bone (BSP) |
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Description: Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an MW ~70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling. Applications: Suitable for use in Western Blot, Immunohistochemistry, RIA and ELISA. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. *Recommended Secondary Antibodies: IHC I1904-43: IgG, X-Adsorbed (Biotin) Pab GtxRb I1904-40E: IgG, H&L (Biotin) Pab GtxRb I1904-46P: IgG, H&L (Biotin) Pab GtxRb Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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