Technical Data
S1013-34A
Sialoprotein, Bone (BSP)
Description:
Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an MW ~70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, RIA and ELISA. Other applications have not been tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

*Recommended Secondary Antibodies: IHC
I1904-43: IgG, X-Adsorbed (Biotin) Pab GtxRb
I1904-40E: IgG, H&L (Biotin) Pab GtxRb
I1904-46P: IgG, H&L (Biotin) Pab GtxRb

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul4°C (-20°C Glycerol)Blue IceHumanRabbit
Concentration:
Not determined.
Immunogen:
Purified human Bone sialoprotein
Purity:
Serum
Form
Supplied as a liquid, serum, 40% glycerol. No preservatives added.
Specificity:
Recognizes Human Bone sialoprotein (BSP). Does not crossreact with human osteopontin or osteonectin by RIA or ELISA. Species Crossreactivity: Rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.