Technical Data
S1013-88A6
SIRT1 (NAD-dependent Deacetylase Sirtuin-1, hSIRT1, SIR2-like Protein 1,SIR2L1 Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. cerevisiae), hSIR2, SIR2L1) (Azide Free)
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Technical Data |
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S1013-88A6 |
SIRT1 (NAD-dependent Deacetylase Sirtuin-1, hSIRT1, SIR2-like Protein 1,SIR2L1 Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. cerevisiae), hSIR2, SIR2L1) (Azide Free) |
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Description: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. [provided by RefSeq] Applications: Suitable for use in ELISA, Immunofluorescence, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1ug/ml-3ng/ml Western Blot: 1:500-1:1,000 Immunohistochemistry (paraffin): 1.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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