Suitable for use in ELISA. Other applications not tested.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
|50ug||4°C (-20°C Glycerol)||Blue Ice||Human||Mouse|
|ovalbumin-conjugated synthetic peptide corresponding to aa28 - aa77 of human silent information regulator 2 homolog (Sirt3)|
|Purified by Protein G affinity chromatography.|
|Supplied as a liquid in PBS, pH 7.2, 40% glycerol.|
|Recognizes Sirt3, a mitochondrial NAD-dependent deacetylase, enzyme involved in the constitutive deacetylation of one or several mitochondrial proteins. The Sirtuin 3 activity could play an important role in the mechanism of the acetylation control of factors directly involved in apoptotic pathways.|
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
1. Schwer, B. et. al. (2002) J. Cell Biol. 158, 647 - 657.|
2. Smith, J.S. et. al. (2002) Methods Enzymol. 353, 282 - 300.
3. Frye, R. (2000) Biochem. Biophys. Res. Commun. 273, 793 - 798.
4. Frye, R. (1999) Biochem. Biophys. Res. Commun. 260, 273 - 279.