		Technical Data
S1014-55T	SMAD9 (SMAD Family Member 9, Smad-9, HGNC:6774, MADH6, Mothers Against Decapentaplegic Homolog 9, MAD Homolog 9, MADH9, SMAD Mothers Against DPP Homolog 9 (Drosophila), SMAD8A, SMAD8B)

Description:
SMAD9 is a member of the MAD-related family of molecules. MAD-related proteins are a recently identified family of intracellular proteins that are thought to be essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide: C-HSEPLMPHNATYPD, representing the internal region of the human protein according to NP_005896.1. Homology: Mouse, Rat, Dog

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.

Specificity:

Recognizes human SMAD9. Species sequence homology: Mouse, Rat, canine

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell. 2003 Jun 13;113(6):685-700. Review. PMID: 12809600