		Technical Data
S1014-67M	Snail Homolog 2 (SNAI2, MGC10182, SLUG, SLUGH, SLUGH1, WS2D)

Description:
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Applications:
Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry (FFPE): 2.5ug/ml. Requires heat-induced antigen retrieval in pH 6.0 citrate buffer.
Western Blot: 1-2ug/ml
Optimal dilution to be determined by researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Purified

Size		Storage	Shipping	Source	Host
50ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~1mg/ml

Immunogen:

Synthetic peptide corresponding to 13aa near the center of human Slug (KLH).

Purity:

Purified

Form

Supplied as a liquid in PBS, 0.02% sodium azide.

Specificity:

Recognizes human Snail Homolog 2 (SNAI2). Species sequence homology: mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.