Technical Data
S1014-67M
Snail Homolog 2 (SNAI2, MGC10182, SLUG, SLUGH, SLUGH1, WS2D)
Description:
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Applications:
Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry (FFPE): 2.5ug/ml. Requires heat-induced antigen retrieval in pH 6.0 citrate buffer.
Western Blot: 1-2ug/ml
Optimal dilution to be determined by researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to 13aa near the center of human Slug (KLH).
Purity:
Purified
Form
Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:
Recognizes human Snail Homolog 2 (SNAI2). Species sequence homology: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.