Technical Data
SNX18 (Sorting Nexin 18, Sorting Nexin-18, FLJ11997, FLJ32560, FLJ61062, MGC150827, MGC150829, SH3 and PX Domain-containing Protein 3B, SH3PXD3B, SH3PX2, Sorting Nexin-associated Golgi Protein 1, SNAG1)
May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:32,000
Western Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabAffinity Purified
100ug-20CBlue IceHumanGoat
Synthetic peptide corresponding to C-KVQRVPLMTVLSF, from SNX18, at C-terminal (NP_443102.2).
Purified by immunoaffinity chromatography.
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Recognizes human SNX18.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Teasdale RD, Loci D, Houghton F, Karlsson L, Gleeson PA. A large family of endosome-localized proteins related to sorting nexin 1. Biochem J. 2001 Aug 15;358(Pt 1):7-16.