Technical Data
S1040-03P
SOCS 3 (Suppressor of Cytokine Signalling 3, SOCS3, SOCS-3, ATOD4, Cytokine-inducible SH2 Protein 3, CIS3, CIS-3, Cish3, MGC71791, STAT-induced STAT Inhibitor 3, SSI3, SSI-3)
Description:
Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 4-6ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
MOLT-4 lysate

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to CPIREFLDQYDAPL, from the C-terminus of the protein sequence according to NP_003946.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:
Recognizes human SOCS3. Species sequence homology: mouse and rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Roberts AW, Robb L, Rakar S, Hartley L, Cluse L, Nicola NA, Metcalf D, Hilton DJ, Alexander WS. Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3. Proc Natl Acad Sci USA. 2001 Jul 31;98(16):9324-9. PMID: 11481489