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Technical Data |
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S4601 |
Sodium butyrate |
1g |
| Biochemicals | Storage: -20°CShipping: Blue Ice |
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A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells. Applications: Suitable for use as a histone deacetylase inhibitor. Other applications have not been tested Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. CAS Number: 156-54-7 Molecular Formula: C4H7O2 . Na Molecular Weight: 110.1 |
Purity: ~99% by HPLC Form: Supplied as a white solid. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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